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Class Notes for Biomedical Sciences at University of Guelph

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BIOM 3090 Lecture Notes - Lecture 11: Parasympathetic Nervous System, Sympathetic Ganglion, Sympathetic Nervous System
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BIOM3090 Lecture 11 January 29, 2019 Somatic = voluntary movement Autonomic = involuntary control (HR) PSNS: Parasymaptheic nervous system Divisions of theAutonomic Nervous System 1. Parasympathetic nervous system (PSNS) A...

Biomedical Sciences
BIOM 3090
Bettina Kalisch
BIOM 3090 Lecture Notes - Lecture 5: Dissociation Constant, Pharmacodynamics, Therapeutic Index
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BIOM3090 Lecture 5 Jan 16, 2019 Drug Receptor Binding The study of pharmacodynamics (the effect of a drug on the body) is based on the concept of drug receptor binding When a sufficient number of receptors are bound in the...

Biomedical Sciences
BIOM 3090
Bettina Kalisch
BIOM 3090 Lecture Notes - Lecture 8: Plasma Protein Binding, Adipose Tissue, Extracellular Fluid
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BIOM3090 Lecture 8 January 23, 2019 Distribution Absorption of a drug is a requisite for establishing adequate blood drug levels, but the drug must also reach the target site in adequate concentrations to be effective Dist...

Biomedical Sciences
BIOM 3090
Bettina Kalisch
BIOM 3090 Lecture Notes - Lecture 6: Active Ingredient, Lipophilicity, Biotransformation
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BIOM3090 Lecture 6 January 21, 2019 Physicochemical Factors in Transfer of DrugsAcross Membranes Most drugs are administered into one body compartment and move to their store of action Drugs must permeate various barriers ...

Biomedical Sciences
BIOM 3090
Bettina Kalisch
BIOM 3090 Lecture Notes - Lecture 7: Subcutaneous Injection, Oral Mucosa, Portal Vein
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BIOM3090 Lecture 7 Routes ofAdministration Enteral: oral (per os; PO) Most common method of administration of drugs Advantages Most convenient for self administration Most economical route Usually safer than injection Mini...

Biomedical Sciences
BIOM 3090
Bettina Kalisch
BIOM 3090 Lecture Notes - Lecture 2: Yin And Yang, Publication Bias
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BIOM3090 Lecture 2 Jan 9 2019 An Introduction to the Treatment of Disease Origins of Medicine in Europe Hipporates (400 BC Greece) Galen (2nd centuryAD Rome) Famous Roman physician to the gladiators Main idea: universe if ...

Biomedical Sciences
BIOM 3090
Bettina Kalisch
BIOM 3090 Lecture Notes - Lecture 10: Pharmacokinetics, Bioavailability, Cyp3A4
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BIOM3090 Lecture 10 Jan 27, 2019 Clinical Pharmacokinetics (PK) Dynamic interactions among drugADME determines plasma concentration of drug and target site concentration Equilibriums exist between drug in plasma and other ...

Biomedical Sciences
BIOM 3090
Bettina Kalisch
BIOM 3200 Lecture 1:

Biomedical Physiology BIOM *3200 S18 Endocrinology The endocrine system is the second of the bodys regulatory systems, other being nervous system. Hormones are chemical messengers that are secreted from endocrine glands or...

Biomedical Sciences
BIOM 3200
Jennifer Monk
BIOM 3010 Lecture Notes - Lecture 4: Myositis, Osteomyelitis, Sprain
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Musculoskeletal Injuries and Disorders Keywords: - Fractures - Sprains - Bursitis - Osteoporosis - Osteomyelitis - Osteoarthritis - Muscle Strain - Tend...

Biomedical Sciences
BIOM 3010
Matthew Vickaryous
BIOM 3010 Lecture Notes - Lecture 3: Multinucleate, Cardiac Muscle, Motor Neuron
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Anatomy of the Muscular System Key Terms: - Muscle Types - Origin, Insertion - Agonist/Antagonist - Muscle Microanatomy - Movement Terminology There are four characteristics ...

Biomedical Sciences
BIOM 3010
Matthew Vickaryous
BIOM 3010 Lecture Notes - Lecture 1: Transverse Plane, Histology, Sagittal Plane
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Introduction to Comparative Anatomy One of the oldest Sciences: - In the 1500s other animals were used in dissection to try and understand our insides Anatomy is the science of the structure of organized bodies: ...

Biomedical Sciences
BIOM 3010
Matthew Vickaryous
BIOM 3010 Lecture Notes - Lecture 2: Clavicle, Shoulder Girdle, Osteoblast
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The Skeletal System Keywords: - Axial skeleton - Appendicular skeleton - Bone structure - Surface features of bones - Osteocytes The Vertebrate Skeleton: Variation of a Common Theme Th...

Biomedical Sciences
BIOM 3010
Matthew Vickaryous
BIOM 4180 Lecture Notes - Lecture 14: Skeletal Muscle, Echocardiography, Ranolazine

Myocardial ischaemia o A reduction in blood supply to the heart, or an increased demand for blood supply that is not met. Not enough nutrients, and waste products not taken away ...

Biomedical Sciences
BIOM 4180
Glen Pyle
BIOM 4180 Lecture Notes - Lecture 16: Oophorectomy, Chest Pain, Triage

Effects of sex on the heart o Risk of CVD higher in women May be due to increased exposure to risk factors (smoking, alcohol consumption) Younger women have lower rates o...

Biomedical Sciences
BIOM 4180
Glen Pyle
BIOM 4180 Lecture Notes - Lecture 12: Regioselectivity, Hypertrophic Cardiomyopathy, Adipose Tissue

Heart failure: heart can not function to meet the demand of the body o Myocardial failure: a defect in cardiac contraction that causes heart failure Problem lies within the heart muscle ...

Biomedical Sciences
BIOM 4180
Glen Pyle

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