EQN 3050 Lecture Notes - Lecture 7: Hyaline Cartilage, Type Ii Collagen, Joint Capsule
1 Feb 2018
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Eqn 3050 lecture 7 jan 30/18. Cells of articulating joint: synoviocytes part of the articulating joint but not cartilage lign the membrane that surrounds the entire articulating joint, chondrocytes main cell in cartilage ; make cartilage matrix (collagen and proteoglycan); Super cial damage to cartilage won"t heal as well as one that goes all the way through. Joint capsule lines with synovial membrase (where you nd synoviocytes metabolically active; produce cytokines, il"s etc; they are among the rst cell type to respond when something is wrong in ammatory environment stimulation) When you remove cartilage layer you get abrasive movement and get heat production can be harmful. Prostaglandin e2 (pge2) ; scape goat of joint disease ; when you give a horse bute (non selective cox1/2 inhibitor) you"re trying to inhibity pge2. Nitric oxide (no) ; along with pge2 is responsible for the horses" perception of pain; so bute blocking these takes away perception of pain.
