HK 3810 Lecture Notes - Lecture 10: Autoregulation, Angiotensin, Endocytosis

• School: University of Guelph
• Department: Human Kinetics
• Course: HK 3810
• Professor: Coral Murrant

Document Summary

2 pressure sensors in carotid arteries (to brain) make sure it is monitored: high pressure barorecptors, carotid artery - carotid sinus, wall of the aorta - aortic arch. Nerve up coordinated center that will change ap frewuency based on stretch. Blood pressure sitting at 100 ap freq telling brain its good. Raise or lower freq deending on whether you raise or lower blood pressure. Slowly adapting sensor slowly adapt over days. If raise bp high for 3-4 days sensors will think thats new normal and shift how sensing things. Projections from barorc medulla (brain stem lots of synapses) Inhibit vasocontricter center and cadioaccellerator center (dec tpr, dec map, dec hr: stimulate cardiodecellerator center (dec hr contractility, hypothalamic nuclei that control adh-vp secretion (nerves from sensor to hypthalamic nuclei (adh-vp is hormone as a placeholder)) Inc map inc ap freq from barorc info to brain stem. Inc h2o loss at kidney inc excrete out of body dec blood volume dec map.