HK 4550 Lecture Notes - Lecture 1: Cyclic Adenosine Monophosphate, Bicarbonate, Chronic Obstructive Pulmonary Disease

• School: University of Guelph
• Department: Human Kinetics
• Course: HK 4550
• Professor: Jeremy Simpson

Document Summary

1. 39 mls of o2/ g of hb (cid:224) 1. 39 is an average (1. 29 1. 36: changes depending on condition (1. 39 is in a lab setting under ideal conditions, when carbon monoxide is bound to hb, oxygen cannot bind to it, co does not bind to the same spot that o2 does on hb, will reduce 1. 39 down (ie. smokers, will have less hb available to carry oxygen if you are a smoker. Mirna is found within adult red blood cells are they doing a function: different mirna in different diseased states, thus are not static, rbc"s have a phospholipid membrane thus need to produce energy and therefore have capabilities of metabolism, have beta receptors on rbc, have secondary messengers on rbc: camp, cgmp, pka, pkg, hb has a phosphate (cid:224) if we increase hb phosphorylation (drugs) we see a shift in the curve to the right (increase p50, decrease o2 affinity) (cid:224) unloading more oxygen to the mb in muscles.