MBG 1000 Lecture Notes - Lecture 8: Ochratoxin A, Mycotoxin, Phenylalanine
21 Nov 2018
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Alleles and recessive traits pt 2: jan 25/17. Molds and mycotoxins: mold species grow on crops (grains; beans) and produce mycotoxins, fungal (myco) toxins produced by molds, didn"t know how to properly store the crops. Ireland/west scotland has mild, wet climate: encourages mold growth, produces ochratoxin a (mycotoxin, when consumed, has variety of side effects, several famines/poor nutrition over centuries, mold infected grains/beans used to prepare food. Ochratoxin a = phenylalanine derivative: causes kidney diseases in adults. Dietary management of pku: reduce the intake of phenylalanine, diet includes protein supplements in which phenylalanine is reduced. Special formula for infants and toddlers: protein mixes for children and adults. Strict adherence to diet during pregnancy; high phe damaging to fetus: artificial sweeteners contain phenylalanine, aspartame (nutrasweet) consists of 2 amino acids: phenylalanine and aspartic acid, understanding the type of environment will help you manage. Eliminate affected genotype: normal- look at big a - 1/3 can be aa.
