MBG 2040 Lecture Notes - Lecture 22: Small Nuclear Rna, Transcription Bubble, Helicase
27 Nov 2016
School
Department
Course
Professor
Document Summary
Transfer of genetic info - central dogma o. One strand of dna of gene used as a template to synthesize a complementary strand of. Example in below diagram the dna sequence: aaa is transcribed into uuu. Translation then converted into amino acids (conversion governed by genetic code) Specifications of a. a. by codons in gene transcript i. e. uuu = Perpetuation of information from generation to generation through high fidelity dna replication. Transcription to produce distinct types of functional rnas. Translation of mrnas into proteins (enzymes, structural proteins, signal molecules) Composed of 3-5 rna molecules and 50-90 proteins o o o. Gene expression in prokaryotes and eukaryote comparison o. The primary transcript (transcription product) matches mrna because processing isn"t required. Sequence of gene is co-linear with those of its mrna and polypeptide chain mrna often polygenetic (aka poly-cistronic) Poly-cistronic is an older name of polygenic - 1 mrna can encode multiple polypeptides (only prokaryotes)
