MBG 2040 Lecture Notes - Lecture 5: Transposable Element, Retroposon, Transposase

• School: University of Guelph
• Department: Molecular Biology and Genetics
• Course: MBG 2040
• Professor: Jim Uniacke

Document Summary

Transposable genetic elements: transposable elements: an overview, transposable elements in bacteria, cut-and-paste transposons in eukaryotes, retroviruses, retro-transposons and retroposons, transposable elements in humans, the evolutionary implication and beneficial applications of transposable elements. Three main types of transposable genetic elements and their mode of transposition: In cut-and-paste transposition, an element is cut out of one site in a chromosome and pasted into a new site on the same or a different chromosome. In replicative transposition (or copy and paste), an element is replicated, and one copy is inserted at a new site; the other copy remains at the original site. In retrotransposition, an element is first transcribed into rna, which is reverse transcribed back into. Dna, followed by insertion of the dna into a new site on the same or different chromosome. Dna molecules are then inserted into new genomic locations. Transposable elements in bacteria: bacterial transposons move within and between chromosomes and plasmids.