MICR 2420 Lecture 12: Lecture 12 Immune System

• School: University of Guelph
• Department: Microbiology
• Course: MICR 2420
• Professor: Lucy Mutharia

Document Summary

Lecture 12: introduction to the innate immune system: protects you from foreign invaders. If it does(cid:374)"t (cid:449)ork properly it (cid:272)a(cid:374) also atta(cid:272)k the host. If you have an infection your lymph nodes must swell. Spleen, thymus and bone marrow are part of this system. System works at the same level each time it meets the pathogen: has no memory, characteristics, present at birth, non-specific, no memory, no amplification, 1st line of defence (0-12h) Survive the defenses of the innate system: exploit host resources and begin to multiply, virulence factors it what the microbe uses to get past the immune system. What systems would you install: perimeter barrier system, a surveillance system, defences for close encounters, bring out the troops, biometric identification system, send a specialist unit after persistent invaders. If all the a(cid:271)o(cid:448)e fails (cid:272)all i(cid:374) the (cid:271)a(cid:272)k up syste(cid:373: physical barriers located at the body: external environmental interface.