MICR 2420 Lecture Notes - Lecture 3: Lysozyme, Peptidoglycan, Acidophile
18 Apr 2016
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Document Summary
Special option the waxy" model mycobacterial cell envelope. Most complex of all bacterial cell envelopes: mycobacteria most famous are m. tuberculosis and m. leprae. Include unusual membrane lipids (mycolic acids: form thick, waxy surface that is exceptionally hydrophobic and resistant to chemicals (and phagocytosis) Resistance to: osmotic lysis detergents drynessmany disinfectants most antibiotics. Can flex to allow movement of molecules. Can act as a scaffold for building synthetic plasma membranes for all kinds of applications. Can act as a template for building inorganic nanocrystal super-lattices for. Sometimes called the slime layer" available option for both g+ and g- models. Consists of as lippery coat of loosely bound polysaccharides. Difficult to stain and thus appear as clear halos around cells. May exist with s-layer ; if so, is foundoutside of the s-layer: in this example, see g+ cell. Has important role in pathogens for preventing phagocytosis/activation of the innate immune system. Thylakoids (only available for gram negative phototrophs)
