MBG 1000 Lecture Notes - Muscular Dystrophy, Nuclear Pore, Nuclear Membrane

• School: University of Guelph
• Department: Molecular Biology and Genetics
• Course: MBG 1000
• Professor: Georgevander Merwe

Document Summary

4 main categories: epithelial, has nucleus, other complex organelles, humans are eukaryotes. Open to outside ducts (lungs, stoumach: muscle, nerve, connective. Mutations affect whether the cell functions normally. Mutation in x-linked gene causes diseased muscle cells. Nucleic acid: dna, rna, genetic material. Surrounded by nuclear envelope: made of inner and outter membrane. Contains nuclear pores: allows for some molecules to move in and out, rrna production required to make proteins. Each chromosome is a compacted dna molecule. Unwinding of dna allows for dna replication and gene expression. Mitosis produces new cells: occurs in somatic cells, all cells but egg and sperm. Apoptosis is cell death that is part of normal development (controlled) Necrosis is cell death that is in response to injury. Cell cycle (sequence of events in cell division) M-phase: dna synthesis (replication, gap for growth, mitosis (nuclear division, prophase, metaphase, anaphase, telephase. Dna replication occurs prior to division in s-phase. Produces sister chromatids (each contains one dna strand)