NUTR 1010 Lecture Notes - Lecture 9: Neural Tube Defect, Macrocytic Anemia, Red Blood Cell

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Lecture 21: wednesday march 5, 2014: folate, plays role in dna synthesis. Critical during first few weeks of pregnancy: folic acid is the active form of folate. Naturally-occurring food folate is converted to folic acid in body with help of vitamin b12. Also consume folic acid in supplements and fortified foods (flour, grain products mandatory fortification with folic acid introduced in north. Rda is about 600 /day to support high rates of cell development for uterus, placenta and fetus (expansion of mom" red blood cell mass) Improper closure of neural tube can lead to ntd. If improper closure happens in spinal cord results in spina bifida. If improper closure happens in brain results in anencephaly (brain not fully developed and really fatal in children) Only moneys, apes, guinea pigs, and fruit bats cannot. Don"t have the right enzyme to do that: what does vitamin c do. Assists in synthesis of dna, neurotransmitters, and some hormones.

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