NUTR 3210 Lecture Notes - Lecture 18: Glutathione Peroxidase, Superoxide Dismutase, Pearson Education
23 Mar 2017
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Document Summary
Reduction-oxidation reactions: reduction-oxidation reaction is a redox reaction. 4 tocopherols saturated side chains with 16 carbons. Vitamin e intake: food sources: nuts, seeds, vegetable oils, leafy grans. Sensitive to food prep and storage, for example roasting nuts decreases vitamin e level. Mostly obtained through plants because stored in fat in animals: rda based on a-tocopherol only. Estimated based on crude tests examining rbc hemolysis (releases haemoglobin) in presence of diluted h2o. (>20% hemolysis = vitamin e deficiency: rdas for vitamin e in mg or iu . Adults (15mg = 22. 4 iu) of rrr a-tocopherol per day. Seen with fat malabsorption disorders or gallbladders removed. Digestion, absorption, & metabolism: absorbed in jejunum, bile salts necessary, npc1l1 transport thought to be involved in uptake, packaged into chylomicrons, cr arrive at the liver, liver makes ttp which is needed to get a-tocopherol packaged into. Vldl: other vitaminers help a bit with anti-oxidant activity but are quickly lost.
