NUTR 3210 Lecture Notes - Lecture 7: Cardiac Muscle Cell, Coronary Artery Disease, Endoplasmic Reticulum

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The striation is the result of myosin and actin arranged in the form of sarcomeres: sarcomeres are the functional contractile unit of the cardiac muscle cell, communications occur in gap junctions. Two major organelles: mitochondria and sarcoplasmic reticulum: the electrical signal produces contraction, it follows calcium induced calcium release. All the i(cid:374)fo is o(cid:374) the slides . The z discs do not move; the myosin pulls the muscle together to contract: what"s happening is the myosin is pulling the actin. The overlapping area is where the actin and myosin are and show darker on the microanatomy. Coronary heart disease leads to high bp heart attacks heart failure. Research is now directed towards prevention versus cure. Build up starts in your late teens and 20s. Angina is due to blood flow restriction. Beta blockers block the beta-adrenergic receptor: they can also be used to calm down individuals. Given to people with stage fright (athletes, musicians, etc)

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