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Lecture 12

NUTR 3210 Lecture 12: Micronutrients Part 1

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NUTR 3210
David Mutch

Micronutrients Bind to Type II Steroid Hormone Receptors and have Global Health Implications Vitamin A Vitamin D Vitamin K Iodine Calcium Phosphorous Fluoride Vitamins and Minerals: The Basics Characteristics for classification as a vitamin: o Exogenous supply is required o Needed in small amounts o Distinct from sugars, fats, and proteins with regards to structure and function o Performs at least one essential biochemical function o When lacking in the diet, a characteristic deficiency disease develops o Organic Main distinction from mineral, which are inorganic Ways to Discuss Micronutrients: Traditional Discussion: o Fat soluble vitamins, water soluble vitamins, and minerals Functional GroupingsPractical Important Discussion o Group I: Micronutrients which control type II steroid hormone receptors and have major global health implications Iodine, Vitamin A, Vitamin D, Calcium, Vitamin K, Phosphorus and Fluoride o Group II: Micronutrients that work together in oxidant defense Vitamin E, Selenium, Vitamin C, Niacin, Riboflavin, Copper, Zinc, Manganese o Group III: Micronutrients that act as enzyme cofactors Thiamin, Niacin, Riboflavin, Vitamin B6, Folate, Vitamin B12, Biotin, Pantothenic acid o Group IV: Iron, copper, and zincrelated divalent cations 1 out of 3 people in developing countries are affected by vitamin and mineral deficiencies o WHO Group I These micronutrients control cellular function through a certain type of process o They control type II steroid hormones Only vitamin A, vitamin D, and Iodine act directly on steroid hormone receptors o BUT, we cannot talk about vitamin D without talking about calcium, phosphorus, and vitamin K (all involved in bone metabolism)
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