NUTR 3210 Lecture Notes - Lecture 11: Glutathione Peroxidase, Unpaired Electron, Tocopherol

• School: University of Guelph
• Department: Nutrition
• Course: NUTR 3210
• Professor: David Mutch

Document Summary

Micronutrients part 2 micronutrients involved in oxidant defense. Reduction-oxidation reactions: reduction-oxidation reaction aka redox reaction. Involves the transfer of electrons between two substrates. Many biochemical reactions are essentially electron transfers: large number of micronutrients have redox functions, the primary electron carriers in the body are nadh and. Fadh2: this is important for the creation of atp. Reactive oxygen species (ros: ros produced as a by-product of the etc when proper electron flow fails (cid:523)~(cid:857)% (cid:494)leakage(cid:495)(cid:524, occurs in o2 rich environment where oxygen can react with electrons, radicals have unpaired electrons. / want to get rid of imbalance so will get rid of electrons. /radicals are produced in any cell that has a mitochondria: mutations in sod = lou gehrig(cid:495)s. Ros are linked to disease: h2o2 converted to h2o by catalase, glutathione peroxidase (selenium dependent enzymes, (owever, ros aren(cid:495)t always bad (cid:523)remember t(cid:859) and t4 production)