NUTR 3210 Lecture Notes - Lecture 1: Standard Deviation
27 Jun 2018
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What are the dietary reference intakes (DRI's)?
oDRI's can essentially be thought of as numbers that reflect how much of a
nutrient should be consumed in order for someone to be healthy, with a healthy state
being related to a specific endpoint, as well as to avoid experiencing harm from
consuming too much or too little of that nutrient.
oThere are several numerical values that are part of the DRI's and as we will see
later, each of these numbers has a different use
oThe DRI's have been published since 1997, and reflect the current state of
scientific knowledge as evaluated by scientists at the institution of medicine in a very
thorough review process
oBased on indicators of good health, prevention of chronic diseases, an adverse
effects of excess intake (when applicable)
o provide values for apparently healthy individuals, rather than clinical
populations
How do we estimate nutrient requirements?
oNutrient requirements are considered as frequency distributions of nutrient
intake needed by individuals within a population to achieve similar end points
oThe data relate to each other with the use of statistical distributions. This graph
is the starting point, there are six elements to be aware of:
Y axis of the figure which shows the percentage of the population that’s
consuming a certain amount of a nutrient
X axis of the figure which is the amount of nutrient required to satisfy
the accepted endpoint that represents health
The middle part of the graph represents the mean nutrient intake of the
population. The graph shows this corresponds to the peak of the curve, and
exactly 50% of the population fall below, and 50% fall below this mean
If everyone were required to consume the mean nutrient intake of the
population, only half of the people would be healthy and this would be the
individuals who fall on the left hand side of the distribution curve
If we move to the left of our mean the values will be negative and if we
move right of our mean the values will be positive. 100% of the population will fall
within -3 to +3 standard deviation from the mean in a normally distributed curve
RDA is the amount of number of the DRI's which corresponds to the
amount of nutrient recommended as the target intake for most nutrients, as it
represents the amount that ensure 97.5% of the population will be healthy. At the
RDA 2.5% will not be healthy with respect to that nutrient.
How is this interpreted with respect to recommended intake?
oEAR -> estimated average requirements: meets the needs of 50% of "healthy"
individuals
oRDA -> EAR +2 standard deviations: meets the needs of 97.5% of individuals
oUL -> tolerable upper limit: above this limit, the individual runs the risk of
toxicity
How do values reflect estimation of risk?
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Document Summary
What are the dietary reference intakes (dri"s)? o. There are several numerical values that are part of the dri"s and as we will see later, each of these numbers has a different use o. The dri"s have been published since 1997, and reflect the current state of scientific knowledge as evaluated by scientists at the institution of medicine in a very thorough review process o. Based on indicators of good health, prevention of chronic diseases, an adverse effects of excess intake (when applicable) o provide values for apparently healthy individuals, rather than clinical populations. Nutrient requirements are considered as frequency distributions of nutrient intake needed by individuals within a population to achieve similar end points o. The data relate to each other with the use of statistical distributions. This graph is the starting point, there are six elements to be aware of:
