NUTR 3210 Lecture 4: Unit 4 - Review of Intermediary Metabolism

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Metabolism overview: general diagram of energy metabolism, showing how paths interconnect and how metabolites are recycled. It is very important to nutritional sciences: tca"s main role is to oxidize coa to co2 and capture energy in form of electrons in nadh. Some e- captured in fadh2 and some substrate level phosphorylation. Nadh and fadh2 donate electrons to components of the etc and potential energy of electrons is used to pump protons out of mitochondria. These return through f1atpase, powering formation of atp. Oxygen accepts electrons at the end of the etc, and the tca cycle and etc will be impaired in low oxygen condition. Metabolic fate of glucose: several possible paths that glucose can be part of as a substrate. The path glucose travels on depends on the cells requirements (i. e. immediate energy needs aerobically or anaerobically vs building energy storage vs biosynthesis/cell division)

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