PATH 3610 Lecture Notes - Lecture 7: Benign Tumor, Radiation Therapy, Immunotherapy

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3-5 of your textbook), and complete the following: hyperplasia refers to, physiologic hyperplasia includes: Compensatory hyperplasia (define: pathologic hyperplasia is nonphysiologic response. Recall hypertrophic cardiomyopathy in the cat (unit 02 pp. 84-86); prostatic hyperplasia is common in older men, and is thought to be associated with declining androgen levels: atrophy: Developmentally, organs may occasionally be underdeveloped (hypoplastic) or even completely undeveloped (aplastic). While these can be functionally important, the pathogenesis of such a lesion is variable: osteoporosis is another example of disuse atrophy. It is the result of bone resorption occurring more rapidly than formation. The lack of estrogen following menopause leads to atrophy of the vaginal epithelium and endometrium: severe malnutrition (protein calorie), as occurs with prolonged anorexia, will lead to atrophy of a variety of tissues, including muscle. Ischemia can also lead to atrophy of tissues. 165-166 (cid:862)dysplasia(cid:863) **: dysplasia is characterized by nuclear abnormalities (increased nuclear size, increased chromatin content, chromatin clumping, etc.

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