PATH 3610 Lecture Notes - Lecture 1: Bone Fracture, Osteopenia, Chronic Kidney Disease

• School: University of Guelph
• Department: Pathology
• Course: PATH 3610
• Professor: Rob Foster

Document Summary

So animals from the desert would have a large medulla. Very easy to see the differences in cat kidneys. Arteries and veins all go to the glomerulus and enter between medulla and cortex. All blood goes to the glomerulus in the cortex first. End artery system = prone to infarct. Nephron = the functional unit of kidney. Kidney ureter bladder urethra (male and female) Feco-oral transmission via undercooked hamburger and drinking water. The product (exotoxin) of the bacteria kill the verol cells. Hemolytic disease (hemolysis = rbc break apart = regenerative anemia) If blocked, no urine is produced, blood supply is stopped = infarct. Kidney does not function at an appropriate level due to > 70% of nephrone function lost. Usually targeted by some toxins and anything that can kill nephrons. Anything that happens to the plumbing system after the kidney. Urea (produced by liver), creatinine (from muscle metabolism), drugs. Azotemia: increased urea and creatinine (nitrogen) in blood.