PATH 3610 Lecture Notes - Lecture 2: Gluconeogenesis, Genetic Predisposition, Peripheral Neuropathy

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Part that produces the enzymes used to breakdown food. Combined with pancreatic juice (produced by glands of the pancreas) and passed into the pancreatic duct. Pancreatic duct joins with the bile duct. Can get blocked by stone and get jaundice (post hepatic) Can replace the enzyme produced (pill or powder) Enzymes secreted into duct and instead of activated in intestine they are activated in the pancreas itself and causes inflammation of pancreas = self digesting. Hemorrhage by elastase (break down elastin in blood vessels) We need a baseline of glucose concentration (energy supply for brain and rbc), has to be maintained as a narrow range in blood. Concentration of glc below the normal reference range. Affect us in the long term rather than short term. Concentration of glc above the normal reference range. Soap made of ash from fires and animal fat. Breaking down fat results in soap formation (fat necrosis) Produce hormones (substances that excites others at a distance)

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