POPM 3240 Lecture Notes - Lecture 7: Tylenol (Brand), Null Hypothesis, Alternative Hypothesis

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Experimental studies: investigators are responseble for assigning study participants to groups & intervening in some way. I. e. exposing them to exposure of interest, administering a treatment. Observational study designs: watch & observe (cross-sectional, case-control, cohort) Experimental/intervention study designs: researcher actively intervenes with some level of intervention with respect to the subjects; 2 main types: Tend to be logistically more di cult to carry out than clinical trials b/c trials involve healthy rather than diseased people. While many develop outcome of interest in short time frame, many others may not develop disease of interest at all or take long time. This occurs if investigating rare diseases (i. e. types of cancer) Clinical vs. field: major di erence is overall goal & level of control. Clinical trial: objective is to evaluate one/more new treatments for disease/condition: have total control over challenge/exposure & environment (overall)

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