POPM 3240 Lecture Notes - Lecture 2: Bone Meal, Dependent And Independent Variables, Breast Cancer Screening

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A state of complete physical, mental, and social well-being, and not merely the absence of disease or infirmity (human) A state of physical and psychological wellbeing and of productivity including reproduction (veterinary) Illness is a subjective state of the person who feels aware of not being well (human) A finite abnormality of structure or function with an identifiable pathological or clinic- pathological basis and with a recognizable syndrome of clinical signs (veterinary) Determinant: any factor when altered produces a change in the frequency or characteristics of the disease (aka. Exposure, risk factor, independent, predictor or explanatory variable suspected of producing the outcome of interest) Outcome of interest: response or dependent variable disease, health/productivity, immune status, pregnancy. Dr. john wilesmith (modern day john snow ) 1985: 1st case reported (down cow with weird signs) 1987: epidemiologic studies started (counting, mapping, relating) The common factor that was found causing this disease was feeding the cows meat and bone meal.

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