POPM 4040 Lecture 7: POPM 4040 Lecture : E.coli
22 Dec 2018
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Document Summary
Epidemiology of escherichia coli in foodborne disease: focus on e. coli o157:h7. Jack in the box outbreak: december 1992-february 1993, raised awareness in u. s. for e. coli o157:h7 as a serious food safety threat, resulted in monumental changes to food safety policy. Jack in the box outbreak: primarily in washington state. Also one death from hus in california traced back to undercooked. / rare hamburgers served in jack in the box restaurants. Most bacteria are beneficial; part of life. Part of enteric flora all animal species and people. Enterohemorrhagic (ehec)* / verotoxigenic (vtec) / shigatoxigenic (stec) Serotypes o157:h7, o26, o111, o121, o104:h4, others. Diffuse adherent (daec) pathogenesis not well understood. Link between o157:h7, hc, and hus (riley et al. Retrospective reviews of human isolates confirm emerging disease. Transmission to humans: sources / transmission: meat (e. g. , ground beef) , other foods of animal origin (e. g. milk) , produce (veg & fruit) Other foods: water , person-to-person , animal-to-person, environmental contamination.
