Class Notes (836,658)
Canada (509,870)
Psychology (3,977)
PSYC 2410 (137)

Neural Basis Disorders of Neurodevelopment.docx

2 Pages
Unlock Document

PSYC 2410
Elena Choleris

Neural Basis of Autism: 1. Run in the family  sibling with autism, 5% likely that other sibling will have autism. 2. In monozygotic twins (exact same DNA), one twin is 60% likely to have autism if the other twin does (may show differences in symptoms, severity etc.). a. Shows that it is not all genetics! 3. Many chromosomes involved: a. Strong evidence for loci on chromosomes 7 and 17. Also evidence for chromosomes 2, 5, 11, 15, 16 and X. 4. Many genes involved: a. Serotonin transporter on chromosome 17 (regulates aggression and social interactions) b. Transcription factor (EN2) on chromosome 7 (regulates thousands of genes, possibly why there are so many genes involved in autism?) c. Genes associated with glutamate (key role in balance in the brain) d. Neuroexin 1 on chromosome 11 (large body of evidence, involved in cell communication) 5. Thalidomide  environmental factor (given to pregnant women for morning sickness, caused a variety of birth detects including higher incidence of autism) a. Whatever goes wrong in autism occurs early in development. 6. Ears are square in shape and lower on head, tops flopped over, ear development is on 20 and 24 day of development which supports argument that whatever happens in autism happens early. 7. Increased risk for propagnosia 8. Different face pattern scanning. Normally we look at eyes while autistic individuals look all over. 9. Under activation of amygdala (normally activates in respon
More Less

Related notes for PSYC 2410

Log In


Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.