PSYC 2410 Lecture 9: Neurodevelopment.docx
1 Dec 2014
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After formation cells need to: (cid:224)environment (e. g. muscle cells, liver cells, neurons, glia: differentiate, migrate, establish functional relation to the appropriate location with other cells. Stem cells: two properties: unlimited divisions without differentiation, potential to differentiate into different cell types, totipotent stem cells, pluripotent stem cells, multipotent neural or glial stem cells, etc. The assumption that this orderliness results from point to point chemoaffinity is challenged by the following two observations: when half the retinal was destroyed and the optic nerve cut, the retinal ganglion cells from the remaining half retina projected systematically over the entire tectum, when half the optic tectum was destroyed and the optic nerve cut, the retinal ganglion cells from the retina projected systematically over the remaining half of the optic tectum. Neurodevelopment: direct gene regulation adhesion and migration). survival (e. g. for cell adhesion molecules involved in cell, neurotrophin release regulation.
