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Toxicology (14)
TOX 2000 (13)
Lecture

REPRODUCTIVE TOX

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Department
Toxicology
Course
TOX 2000
Professor
Aaron Witham
Semester
Fall

Description
Reproductive tox: - Chemicals can alter many functions of the reproductive system; many different systems, many targets Endocrine functions - Prdocution of sex hormones necessary for sexual maturation and successful reproduction o Responsible for gametogenesis o Reproductive organ function o Reproductive cycles Germ cell functions - Genes transmit genetic info Many stages/points of failure in reproduction - Female cycle 9hormone imbalance o LH/FSH/estrogen/progesterone; damage to either the follicle or the oocyte o Spermatogenesis in males (horomone imbalance LH/FSH/testosterone; impaired or damaged sperm production) o Fertilization (sperm, mobility, egg viablitiy, physical act of ejaculation) o Fetal development (DNA damage; hormonal development, toxic substances; placental barrier) o Parturition/birth (anoxia, physical birth problems) o Laction (passage of toxic substances in milk) Throughout th
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