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Class Notes for Toxicology at University of Guelph

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TOX 4000 Lecture Notes - Lecture 1: Toxicology Testing, Percutaneous, Peritoneum

Lecture 1: Principles Sept. 10 Toxicology: the study of the adverse effects of chemical or physical agents on living organisms Why study medical toxicology: 1. Mechanistic toxicology Identifying and u...

Toxicology
TOX 4000
Craig Bailey
TOX 4000 Lecture Notes - Lecture 2: Xenobiotic, Sarin, Circulatory System

Lecture 5: ToxicodynamicsMechanisms of Toxicity Sept. 19 Benefits of studying mechanisms of toxicity 1. Interpret descriptive toxicity studies 2. Estimate probability that a xenobiotic is toxic 3. Develop plan to mitigate ...

Toxicology
TOX 4000
Craig Bailey
TOX 4000 Lecture Notes - Lecture 4: Glutathione Reductase, Uridine Diphosphate, Glutathione

Lecture 4: phase 2 reactions Sept. 17 But: o Xenobiotic may be eliminated after phase 1 o Xenobiotic may be conjugated by phase 2 directly Conjugation reactions: Glutathione conjugation Glucuronida...

Toxicology
TOX 4000
Craig Bailey
TOX 4000 Lecture Notes - Lecture 5: Cytochrome P450, Xenobiotic, Toxicokinetics

Lecture 2: Toxicokinetics Sept. 12 Hendersonhasselbach equation o If a toxicant is an organic acid or base, absorbed by simple diffusion in the part of the GI tract where it exists in its most lipidsoluble (nonionized) for...

Toxicology
TOX 4000
Craig Bailey
TOX 2000 Lecture 6: Chemical Toxicology
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Toxicology
TOX 2000
Aaron Witham
TOX 2000 Lecture Notes - Lecture 5: Ahor
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Toxicology
TOX 2000
Aaron Witham
TOX 2000 Lecture 4: Chemical Toxicology
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Toxicology
TOX 2000
Aaron Witham
TOX 2000 Lecture 3: Regulatory Toxicology
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Toxicology
TOX 2000
Aaron Witham
TOX 2000 Lecture 2: Regulatory Toxicology
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Toxicology
TOX 2000
Aaron Witham
TOX 2000 Lecture 1: Scanned Documents

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Toxicology
TOX 2000
Aaron Witham
TOX 2000 Lecture Notes - Lecture 37: Central Nervous System, Clostridium, Motilin

Biotransformation Fundamental Concepts for Biotransformation How the body deals with environmental xenobiotics, including compounds present in food. Lipid soluble drugs are poorly excreted in the urine and tend to...

Toxicology
TOX 2000
Kathryn J Stuttaford
TOX 2000 Lecture Notes - Lecture 34: Water–Electrolyte Imbalance, Aglycone, Protein Structure

Tox2000 Final Exam Study Guide Introduction Toxicity is inherent to life All chemicals either natural or manmade have the capacity to be toxic at high enough concentrations Many species of plants, animals and bacteria have...

Toxicology
TOX 2000
Kathryn J Stuttaford
TOX 2000 Lecture Notes - Lecture 12: Prostaglandin, Phagocytosis, Oncology

Biotransformation Fundamental Concepts for Biotransformation How the body deals with environmental xenobiotics, including compounds present in food. Lipid soluble drugs are poorly excreted in the urine and tend to store in...

Toxicology
TOX 2000
Torin Huzil
TOX 2000 Lecture Notes - Lecture 12: Dissociation Constant, Cytoplasm, Antibody

Tox2000 Final Exam Study Guide November 2014 Introduction Toxicity is inherent to life All chemicals either natural or manmade have the capacity to be toxic at high enough concentrations Many species of plants, animals and...

Toxicology
TOX 2000
Torin Huzil
TOX 4100 Lecture Notes - Gastrointestinal Tract, Stratified Squamous Epithelium, Trichothecene

TOX*4100. Written by Garry Go Gastro-Intestinal Toxicity Some of the major functions of the alimentary tract include digestion, absorption, elimination, and defence. Characteristic of the upper alimentary tract is a st...

Toxicology
TOX 4100
Patricia Turner

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