ZOO 3000 Lecture Notes - Lecture 19: Endorphins, Immunohistochemistry, Autocrine Signalling

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There are 3 target types: target is through bloodstream endocrine control (a, target is adjacent or nearby paracrine control (b, target is same cell that secretes autocrine control (c) There are 4 chemical and structural categories of hormones: peptides processed from proteins, steroids derived from cholesterol, amines derived from amino acids, eicosanoids derived from arachidonic acid. Transport of hormones to target cells commonly involves carrier proteins: hormones after biological activity of target cells via interactions with their receptors, peptides and most amines bind to cell surface receptors. Steroids and thyroid hormones bind to intracellular and/or cell surface receptors. Endocrine cells and glands across vertebrates: only a few major endocrine glands are conserved across vertebrates, hypothalamus, pituitary and pineal gland. The gonads are involved in the production of sex steroids across vertebrates. In many vertebrates endocrine cells are scattered in non-endocrine organs.

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