BGEN 3020 Lecture Notes - Lecture 12: Tetraplegia, Epiglottis, Phrenic Nerve

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Acidosis increase in h+ ions, therefore decrease in ph. Alkalosis decrease in h+ ions, therefore increase in ph. New equation for acid/base physio by goljan: ph = [hco3. Increase in bicarb = increase ph = metabolic alkalosis. Decrease in bicarb = decrease ph = metabolic acidosis. Increase pco2 = decrease ph = respiratory acidosis. Decrease pco2 = increase ph = respiratory alkalosis. Compensation = bodies attempt to try to maintain a normal ph (which it never does). If we decrease the nominator, we have to decrease the dominator in order for the equation to stay the same. Therefore, we have to blow off the co2 (hyperventilation): ventilation is a co2 term! Hyperventilation = increase in respiratory rate allows for the blowing off of co2, therefore results in respiratory alkalosis. For the treatment of respiratory alkalosis is to give the pt a paper bag and ask to breath in it, b/c then they are re-breathing their own co2.

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