BGEN 3020 Lecture Notes - Blood Transfusion, Enzyme Assay, Big Bite

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When you do the corrections for the anemia and look for polychromasia; if correction is less than. 2%, it is a bad response (bm not responding correctly). First two things you see: early ida and acdz. Remember that you have to have a normocytic anemia first to become microcytic. Therefore, with a decreased ret ct (ie less than 2%), must include microcytic anemia"s in the differential, and you need to get a ferritin level. Ida goes through diff stages: first thing that happens decreased ferritin, then fe decreases, tibc increased, % sat decrease, and still won"t have anemia. Then you get mild normocytic anemia, and eventually microcytic anemia. Athletes that dope" are given epo, to increase rbc"s to allow more o2 delivery to body. Mechanisms of hemolysis 2 ways to kill an rbc: Normocytic anemias with corrective ret ct about 3%: extravascularly (outside of the bv).

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