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Lecture 24

BIOL 1000 Lecture 24: Lecture 24
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Department
Biological Sciences
Course Code
BIOL 1000
Professor
Kevin G.Scott

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o982 Steps 5-9 – the energy payoff phase – yield energy 2 NADH moecules are produced for each initial glucose molecule, 4 ATP molecules are  generated First phase used 2 molecules of ATP, net gain is 2 for each glucose  molecule  The 2 glucose molecules from glycolysis account for only 6% of energy that a cell can harvest from  glucose The 2 NADH molecules (step 5) account for another 16% Stored energy is not available for use in the absence of O 2 (See page 107 for details on all 9 steps of glycolysis)  The citric acid cycle completes the oxidation of organic molecules, generating many NADH and FADH 2 molecules Citric acid cycle is often referred to as the Krebes cycle Only the 2-carbon acetyl part of the acetyl CoA molecule enters the citric acid cycle The coenzyme A splits off an is recycled Each following step is catalyzed by a specific enzyme that is located in the mitochondrial matrix or embedded in the inner membrane  The 2-carbon acetyl group and a 4-carbon oxaloacetate are joined to form a 6-carbon molecule,  citrate (ionized, negatively charged form of citric acid) Citrate is processed through a series of redox reactions 2 carbon atoms are removed as CO 2 Oxaloacetate is regenerated (“cycle”)  Pays much bigger energy for the cell co
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