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BIOL 1000 (60)
Lecture 39

BIOL 1000 Lecture 39: Lecture 39
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Department
Biological Sciences
Course
BIOL 1000
Professor
Kevin G.Scott
Semester
Fall

Description
o|82 ▪ RNA polymerase binds to sigma factor ▪ DNA complex and transcription can begin o 2) Elongation – RNA grows longer ▪ ▪ RNA strand peels away from DNA template 2 Separated DNA strands go back together ▪ o 3) Termination – RNA polymerase reaches a sequence of bases in DNA called terminator Signals end of the gene ▪ Polymerase molecule detaches from RNA molecule are gene • Transcription also makes 2 other kinds of RNA that are involved in building polypeptides o Messenger RNA, transfer RNA, ribosomal RNA 10.10 Eukaryotic RNA is Processed Before Leaving the Nucleus as mRNA • Messenger RNA (mRNA) = RNA that encodes amino acid sequences Conveys genetic messages from DNA to translation machinery of the cell Transcribed from DNA, information in mRNA is transcribed into polypeptides In prokaryotic cells, translation and transcription occur in cytoplasm  In eukaryotic cells, mRNA molecule exits the nucleus via nuclear pores, and enters the cytoplasm Where machinery for polypeptide synthesis is located Eukaryotic transcripts are modified before leaving the nucleus are mRNA  E.g. addition of extra nucleotides to ends of RNA transcript (small cap at one end, long tail at other end) End cap and tail facilitate export of mRNA from nucleus, protect mRNA from attack by cellular  enzymes, & h
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