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Lecture 41

BIOL 1000 Lecture 41: Lecture 41

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Biological Sciences
BIOL 1000
Kevin G.Scott

o78P o Completed polypeptide is freed from last tRNA Ribosome splits into separate subunits After translation, mRNA, tRNA and ribosomal subunits are all reused 10.15 Review: The Flow of Genetic Information in the CelRNAs DNProtein 1) Transcription – (DNA  RNA): mRNA is synthesized/transcribed from DNA template Occurs in nucleus of eukaryotic cells, mRNA must travel from nucleus to cytoplasm Prokaryotes – occurs in cytoplasm  2-5) Translation – (RNA Protein): all 4 steps occur in cytoplasm Several ribosomes may work on the same mRNA molecule at once o As polypeptide is made, it coils/folds into 3D shape Several polypeptides come together to form a protein (quaternary structure) These are the main processes whereby genes control the structures/activities of cells *The way genotype produces the phenotype  Sequence of nucleotides in DNA (gene) serve as a template, dictating transcription of  complementary sequence of nucleotides in mRNA mRNA dictates linear sequence in which amino acids assemble to form specific polypeptide Proteins that form from polypeptides determine appearance/capabilities of cell & organism Chapter 12: DNA Technology & Genomics Genes Can Be Cloned in Recombinant Plasmids Biotechnology = manipulation of organisms or their components to make useful products  o Dates back to dawn of civilization o E.g. use of microbes to make wine, beet, and cheese & selective breeding of livestock  DNA technology = modern laboratory techniques for studying and manipulating genetic mate
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