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Lecture 27

BIOL 1020 Lecture 27: Lecture 27

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University of Manitoba
Biological Sciences
BIOL 1020
Joy Stacey

Lecture 27 Linked Genes Morgan had fruit flies: wild type (gray body, normal wings) b+ b+ (body color) vg+vg+ (normal wings) Mutant = black body bb vgvg Morgan did test cross: ended up with b+b vg+vg Crossed F1 female with mutant male (can only produce one type of gamete) F1 female can produce four different gametes Predictions: If they are located on different chromosomes predicted 1:1:1:1 (wild type, blackvestigial, grayvestigial, blacknormal) If genes are located on the same chromosome and parental alleles are always inherited together 1:1:0:0 Got the 965:944:206:185 ratio Morgan found that body color and wing size are usually inherited together in specific combinations (parental phenotypes) He noted that these genes do not assort independently, and reasoned that they were on the same chromosome. However, nonparental phenotypes were also produced Understanding this result involves exploring genetic recombination, the production of offspring with combinations of traits differing from either parent (two traits that did not exist together in either of the parents) Genetic Recombination and Linkage The genetic findings of Mendel and Morgan relate to the chromosomal basis of recombination Recombination of Unlinked Genes: Independent Assortment of Chromosomes (mendel) Mendel observed that combinations of traits in some offspring differ from either parent Offspring with a phenotype matching one of the parental phenotypes are called parental types Unlinked genes are independent assortment Offspring with nonparental phenotypes (new combinations of traits) are called recombinant types, or recombinants A 50 frequency of recombination is observed for any two genes on different chromosomes o Eg. Yellowround heterozygous parent crossed with green wrinkled homozygous recessive parent Yellowround and green wrinkled are parentaltype
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