BIOL 1020 Lecture 19: Lecture 19

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BIOL 1020 Full Course Notes
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BIOL 1020 Full Course Notes
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During s phase chromosome replicates becomes double stranded-sister chromatids. Mitosis= division of eukaryotic cells to make genetically identical cells. In g2- chromatin in nucleus(uncondensed dna- 2 stands) In prophase get clear double stranded chromosomes easily visible- consist of two sister chromatids- attached at centromere. Nuclear envelope disappears- beginning to migrate along middle plate. Chromosomes line up along the middle of the cell. Spindle apparatus attaches- splits chromosomes to poles of cell single stranded chromosomes. Apparatus of microtubules that controls chromosome movement during mitosis. During prophase, assembly of spindle microtubules begins in the centrosome, the microtubule organizing center. The centrosome replicates, forming two centrosomes that migrate to opposite ends of the cell, as spindle microtubules grow out of them. Only spindles that come half way attach to chromosomes- attach on the kinetochore. An aster (radial array of short microtubules) extends from each centrosome the spindle includes the centrosomes, the spindle microtubules, and the asters.

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