BIOL 1030 Lecture Notes - Lecture 15: Excitatory Postsynaptic Potential, Inhibitory Postsynaptic Potential, Chemical Synapse
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7 May 2017
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Lecture 15: action potentials propagate down the neuron. They are present only in the presynaptic terminals: the wave of depolarization travels down the length of the neuron. Calcium causes them to move to the end (plasma membrane) of the presynaptic terminals. In which case the ligands are the neurotransmitters: there are two important neurotransmitters for the situation studied. It would then return to resting state: if the acetylcholine release occurs a short time after the first release this can build onto the depolarizations, collectively these depolarizations caused by acetylcholine are known as epsps (excitatory postsynaptic potential). Depolarizations makes the neuron closer to threshold so is referred to as excitatory: a second important neurotransmitter is gaba. On the postsynaptic cell are ligand-gated chlorine (cl-) channels which opens when the ligand gaba is bound to the channel: that allows chloride to move down its concentration gradient (into the cell).
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