MBIO 3010 Lecture Notes - Lecture 23: Hyperventilation, Mycoplasma Pneumoniae, Sputum

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Lysogenized - latent virus - inserts itself into the host genome. Look at the genome and see in you can nd the pathogen dna inside host dna. Makes viral a protein (active protein) - inhibits protein synthesis. Bunch of dead cells in a lump. Paralysis of soft palate and regurgitation of liquids. Upper digestive tract - leads to choking. Antibiotics wont solve the problem, its a viral protein thats causing the disease! antibiotics would cause more harm (lysis of bacteria will release more toxin) Must utilize toxin molecule -> inject into horse - collect serum and will have antibodies. Combination with pertussis, tetanus, polio and haemophilus in uenzae b. Attaches to and multiples in dilated respiratory mucosa. Early phase ~ virology upper rt infections. Fever uncommon (localized, not systemic), paroxysms of coughing. A-b type - a-subunit: adp - ribosyl transferase that catalyzes transfer of adp-ribose from nad to host cell proteins, affects signal transduction.

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