MBIO 3010 Lecture Notes - Lecture 28: Headache, Diplococcus, Encephalitis
28 Dec 2016
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Females - 50% chance of infection post single encounter. Even greater chance of getting a second infection. Ophthalmia neonatorum - new born eye infection. Use co2 for proper growth - grows best at low oxygen concentration. 97 million new cases per year, worldwide. Occurrences started going down after the discovery of hiv, now it will most likely go up again due to resistance to antibiotics. Aids attachment to human mucosal epithelium; contains constant and hyper variable regions - analogous to igs that contribute to antigenic diversity in gonococci. Forms pores through outer membrane; antigenic; speci c serotypes associated with virulence. Serotypes - different strains that must have different antibodies against it. Core contains enzyme; release by cell to destroy iga1. Anorectal (purulent discharge), pharyngeal (sore throat) & ophthalmic infections (common in new borns and self-inoculation) Urethral discharge from symptomatic males with urethritis -> gram negative diplococci inside pmns, diagnostic.
