ACB 330 Lecture Notes - Lecture 14: Cytoskeleton, Gastrulation, Protein Kinase

• School: U of S
• Department: Anatomy and Cell Biology
• Course: ACB 330
• Professor: Kulyk William

Document Summary

Segmental body plan: maternal effect (polarity) genes, transcribed during oogenesis in nurse cells. With effects from follicle cells: encoded maternal mrna that establish a polarity, segmentation genes, zygotically transcribed, determine number and polarity of segments, homeotic genes, zygotically transcribed, determine distinct identities of body segments. Dorsal-ventral axis: during oogenesis, oocyte nucleues is near gurken mrna, translated gurken is growth factor that activates (cid:862)torpedo" o(cid:374) folli(cid:272)le (cid:272)ells at posterior, post. These direct cells to differentiate into mesoderm of ventral furrow. (cid:272)(cid:895) dorsal tf i(cid:374)hi(cid:271)it (cid:862)dpp(cid:863) a(cid:374)d (cid:862))e(cid:374)(cid:863) that spe(cid:272)if(cid:455) dorsal tissue types d(cid:895) i(cid:374)ter(cid:373)ediate [] (cid:272)auses (cid:862) og(cid:863) a(cid:374)d (cid:862)rho(cid:863) ge(cid:374)es to (cid:271)e activated. These genes promote differentiation of neurogenic ectoderm (cid:894)fl(cid:455)"s ventral nerve cord) Causing another gradient: bicoid binds to 3utr of caudal mrna and blacks translation, causing 3 tf in zygote to lead to gradient ( bicoid, hunchback and caudal, during syncytial stage, maternal bicoid and hunchback tf enter nucleus at.