ACB 406.3 Lecture 4: Cartilage and Bone

• School: U of S
• Department: Anatomy and Cell Biology
• Course: ACB 406.3
• Professor: Helen Nichol

Document Summary

Contains no blood vessels or nerves nutrition is from diffusion: thickness affects diffusion. Chondroblasts = rise from mesenchymal stem cells in the embryo and from chondroprogenitor cells in the perichondrium. Synthesize and secrete all components of the matrix, including type ii collagen. Mature cells occupy lacunae often organize into isogenous groups of sister cells. Capsular matrix and inter-territorial matrix have different compositions capsular matrix is more basophilic. As chondrocytes mature: nucleus becomes more heterochromatic, nucleolus is smaller, protein synthesizing machinery (rer, golgi) and mitochondria are reduced, may accumulate lipid droplets. Types of cartilage: hyaline (glass, articular cartilage (a type of hyaline, elastic cartilage (yellow, fibrocartilage (white) No perichondrium no regeneration ribs, trachea, bronchi, larynx, nasal septum. Pinna of ear and ear (not common) elastic fibers. Dense ct alternating w/ layers of dense intervertebral discs, collagenous fibers w/ fibroblasts meniscus of knee. Some joints, some large isogenous groups tendon and ligament. *type ii collagen is found in all cartilages.