Bones are dynamic organs - growing and continually remodeling throughout life. The specific cells
of bone are osteoblasts, osteocytes, and osteoclasts. It has been postulated that osteoblasts are
derived from mesenchymal stem cells called osteoprogenitor cells. It has recently been proven that
osteoclasts originate in bone marrow and probably represent members of the mononuclear
• Osteoprogenitor cells (AKA OPCs) are determined osteogenic precursor cells which
develop into chondroblasts (produce cartilage), osteoblasts (produce bone), or fibroblasts
(produce fibrous connective tissue) depending on various factors.
• Osteoblasts are the immature cells o