Osteocytes, Osteoblasts & Osteoclasts

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Department
Anatomy and Cell Biology
Course
ACB 221
Professor
Keith Russell
Semester
Fall

Description
Bones are dynamic organs - growing and continually remodeling throughout life. The specific cells of bone are osteoblasts, osteocytes, and osteoclasts. It has been postulated that osteoblasts are derived from mesenchymal stem cells called osteoprogenitor cells. It has recently been proven that osteoclasts originate in bone marrow and probably represent members of the mononuclear phagocyte system. • Osteoprogenitor cells (AKA OPCs) are determined osteogenic precursor cells which develop into chondroblasts (produce cartilage), osteoblasts (produce bone), or fibroblasts (produce fibrous connective tissue) depending on various factors. • Osteoblasts are the immature cells o
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