ACB 330 Lecture Notes - Lecture 15: Blastoderm, Syncytium, Homeobox

• School: U of S
• Department: Anatomy and Cell Biology
• Course: ACB 330
• Professor: Kulyk William

Document Summary

Uses bicoid, hunchback and caudal genes (cid:862)torso(cid:863) is a ter(cid:373)i(cid:374)al group that (cid:272)o(cid:374)trols (cid:862)a(cid:272)ro(cid:374)(cid:863) a(cid:374)d (cid:862)telso(cid:374)(cid:863) (cid:862)torso(cid:863) (cid:373)rna is deposited via (cid:374)urse (cid:272)ells i(cid:374) ooge(cid:374)esis activated by torso protein after fertilization an inserted into pm around the whole egg. Activated at only ant/post ends of zygote (cid:862)tailless(cid:863) a(cid:374)d (cid:862)hu(cid:272)k(cid:271)ei(cid:374)(cid:863) are (cid:373)ade i(cid:374) the a(cid:374)t/post e(cid:374)ds. Segmentation genes (gap genes/ pair-rule/segment polarity genes): zygotically transcribed. Bicoid, hunchback and caudal activate the gap genes. 9 total gap genes all code for tf. Each gap tf is expressed in 1 or 2 broad spatial domains. Hairy, even skipped, runt, fushi tarazu, odd paired, odd skipped, sloppy paired, paired. Each genes is expressed as a series of 7 vertical stripes. Serially ordered domains of gene expression along ant- post axis. They set up boundaries in syncytial blastoderm stage. Half of 1 segment and ant half of 1 segment. Lots of enhancers on the even skipped gene.