ANBI 360.3 Lecture Notes - Lecture 20: Canadian Veterinary Medical Association, Aluminium Hydroxide, Viral Disease
20 Jun 2018
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LECTURE 20!
!
Adjuvants!
and adjuvant is a substance that is added to a vaccine to increase its activity!
oil adjuvants create a depot of antigen that is slowly released!•
irritant adjuvants, such as aluminum hydroxide, cause body to recruit and amplify the immune •
response!
Almost always a liquid or extender !
the immune system responds best to organisms which are actively infecting the host!•
killed vaccines are not as immunogenic and therefore need an adjuvant to "help"!•
!
Freund`s Adjuvant!
inactivated and dried mycobacteria in mineral oil!•
forbidden in human now!•
rarely used in animals because of painful injection site reactions!•
!
Viral disease prevention!
viruses are small particles of nucleic acid enclosed in a protein shell!•
viruses gain access into cells via receptors and take over cell`s metabolism to produce viral •
products!
treatment of viral diseases consists of supportive therapy!•
prevention through vaccination !•
!
Duration of immunity after vaccination!
most provinces and/or countries formerly required yearly rabies vaccination of dogs and cats!•
most cat vaccinations last 4-7 years!•
Canadian veterinary medical association does not provide a "schedule"!•
!
Pfizer study!
!
adolescent, puppies or kittens this does not apply!
this is why they need a booster!•
!
how often should you vaccinate?!
primary immunizations!•
at least one before leaving the breeder)!◦
poster at 1 year!•
after that ( adult) : every 3 years!•
!
risk of over vaccination:!
injection site cancer!•
allergic reactions, fever!•
!
Core Vaccines!
vaccines that protect against disease to which a large proportion of the population is •
susceptible!
list will vary with place and time!•
!
Panleukopenia!
caused by a parvovirus!•
Document Summary
Inactivated and dried mycobacteria in mineral oil forbidden in human now rarely used in animals because of painful injection site reactions. Almost always a liquid or extender the immune system responds best to organisms which are actively infecting the host killed vaccines are not as immunogenic and therefore need an adjuvant to help Duration of immunity after vaccination most provinces and/or countries formerly required yearly rabies vaccination of dogs and cats most cat vaccinations last 4-7 years. Canadian veterinary medical association does not provide a schedule Core vaccines vaccines that protect against disease to which a large proportion of the population is susceptible list will vary with place and time. Bordatelloisis ( kennel cough) lyme disease ( from ticks) Giardiasis ( beaver fever, does not stop infection but reduces shedding of cysts) coronavirus mostly for high risk environments such as large dog shows) Live bordetella squirted between gums and test- clings to tracheal lining.
