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Class Notes for Health Sciences at University of Saskatchewan

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HSC 350 Lecture Notes - Lecture 2: Tentorium Cerebelli, Epineurium, Migraine
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HSC 350.3 Fundamentals of Neuroscience January 10, 2017 THE MENINGES (3 LAYERS) 1) Dura mater: Thickest, outermost layer, protective, impermeable. Has 2 layers which are closely ...

Health Sciences
HSC 350
Sean Mulligan
HSC 350 Lecture 12: March 12, 2015

Cerebellar Function The cerebellar function detect the difference or motor error between the intended movement and the actual movement It interact with the upper motor neuron to reduce motor error Correction of motor er...

Health Sciences
HSC 350
Sean Mulligan
HSC 350 Lecture Notes - Lecture 11: Pars Compacta, Medium Spiny Neuron, Substantia Nigra

The Basal Ganglia These nuclei are important in the control of movement ; the selection and initiation of willed movements. They provide ‘supervisory control’ by regulating the activity of upper motor neurons. They respond...

Health Sciences
HSC 350
Sean Mulligan
HSC 350 Lecture Notes - Lecture 10: Reticular Formation, Upper Motor Neuron, Alpha Motor Neuron

The Motor Unit Motor Unit - Each alpha motor neuron synapse with multiple fibers within the muscle. The motor unit is defined as alpha motor neuron and the muscle fibers it contacts Neural control of strai...

Health Sciences
HSC 350
Sean Mulligan
HSC 350 Lecture Notes - Lecture 9: Amyotrophic Lateral Sclerosis, Synaptic Plasticity, Dopaminergic Cell Groups

Neurogenesis Neurogenesis undergoes five developmental stages 1. Proliferation:  Multipotent neural stem cell gives rise to intermediate precursor ‘transit amplifying cell’ that divides asymmetrica...

Health Sciences
HSC 350
Sean Mulligan
HSC 350 Lecture Notes - Lecture 10: Ampa Receptor, Dendritic Spine, Protecting Group

March 26, 2015 What is a caged compound Are biological signalling molecule whose active functionality has been chemically masked with a photo removable protecting group. They are biologically inert precursors of active mol...

Health Sciences
HSC 350
Sean Mulligan
HSC 350 Lecture Notes - Lecture 8: Pars Compacta, Medium Spiny Neuron, Lateral Globus Pallidus

The Basal Ganglia The basal ganglia refer to a large and functionally diverse set of nuclei that are important in motor control. They influence movement by regulating the activity of upper motor neurons not projecting dir...

Health Sciences
HSC 350
Sean Mulligan
HSC 350 Lecture Notes - Lecture 5: Interaural Time Difference, Dorsal Cochlear Nucleus, Sound Localization

The Auditory System Sound Acquisition The external ear gathers sound energy and focuses it on the eardrum (tympanic membrane). The middle ear functions to ensure transmission of sound energy across the air-fluid boundary ...

Health Sciences
HSC 350
Sean Mulligan
HSC 350 Lecture Notes - Lecture 4: Visual Field, Lateral Geniculate Nucleus, Visual Cortex

The Visual System The Retina Comprises complex neural circuitry that converts the graded electrical activity of photoreceptors into action potentials that travel to the brain via axons of the optic nerve (Cranial nerve II...

Health Sciences
HSC 350
Sean Mulligan
HSC 350 Lecture Notes - Lecture 6: Semicircular Canals, Vestibular Nerve, Otolith

The Vestibular System The vestibular system has important sensory functions, contributing to the perception of self-motion, head position, and spatial orientation relative to gravity. It also serves important motor functio...

Health Sciences
HSC 350
Sean Mulligan
HSC 350 Lecture Notes - Lecture 3: Olfactory Bulb, Olfactory Receptor, Adenylyl Cyclase

THE OLFACTORY SYSTEM The olfactory system abides by the same basic principle that governs other sensory modalities --stimuli at the periphery are transduced and encoded by receptors in to electrical signals, which are then...

Health Sciences
HSC 350
Sean Mulligan
HSC 350 Lecture Notes - Lecture 2: Arcuate Fasciculus, Efferent Nerve Fiber, Basal Forebrain

ORGANIZATION OF THE NERVOUS SYSTEM 1. NEURAL CIRCUITS == Neurons organized into ensembles that process specific kinds of information 2. NEURAL SYSTEMS == Circuits that process similar types of information th...

Health Sciences
HSC 350
Sean Mulligan
HSC 350 Lecture Notes - Lecture 2: Retinal Ganglion Cell, Outer Plexiform Layer, Ganglion Cell Layer

January 26, 2016 - Light travels from the optic nerve; from the ganglion cell layer toward the pigment epithelium. - Light travels from the optic nerve; from the ganglion cell layer toward the pigment ep...

Health Sciences
HSC 350
Sean Mulligan
HSC 350 Lecture Notes - Lecture 1: Dural Venous Sinuses, Superior Sagittal Sinus, Choroid Plexus

Physiological Responses of the cerebrovasculature Human brain has high metabolic rate & oxygen requirements = - ONLY 2% of TOTAL BODY WIEGHT BUT RECEIVES ~ 15% CARDIAC OUTPUT & CONSUMES 20% of the oxyge...

Health Sciences
HSC 350
Sean Mulligan
HSC 350 Lecture Notes - Lecture 1: Anterior Spinal Artery, Posterior Spinal Artery, Superior Sagittal Sinus

The Vascular System The brain must maintain tight regulatory control over the delivery of oxygen, glucose and other nutrients and the removal of CO2, and other metabolic products. The cerebral vasculature has unique anatom...

Health Sciences
HSC 350
Sean Mulligan

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