MCIM 321 Lecture Notes - Lecture 14: Thymidine, Growth Factor, Thymus

• School: U of S
• Department: Microbiology and Immunology
• Course: MCIM 321
• Professor: Bretscher Peter

Document Summary

Nature of, and assays for, cell mediated immunity and the role of the antigens. We have seen that pasteur and others developed the means to vaccinate against various. Koch prepared antigen extracts of cultures of m tuberculosis in the hope that the extract of the major histocompatibility complex (mhc) in the rapid rejection of grafts. The discovery of cell-mediated immunity pathogens and toxins in the late nineteenth century. A major disease of that era was tuberculosis, caused by the tubercle bacillus, mycobacterium tuberculosis. The organ most commonly affected is the lungs. It was koch who first isolated this bacterium and who demonstrated that it caused tuberculosis. could be used for vaccination. A more purified protein derivative, known as ppd or tuberculin, can be used to assess whether an individual is immune to the bacterium. The antigen-elicited inflammatory response due to ige antibodies occurs in minutes and is called immediate. Hypersensivity, whereas tuberculin sensitivity is the prototype of a delayed type.