MCIM 224 Lecture Notes - Lecture 9: Famciclovir, Penile Cancer, Gardasil

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Nucleic acid core surrounded by a protein (capsid) coat. Possible outcomes of a virus reproducing in a host cell: Act at various steps during viral life cycle. Viruses can cause damage to host tissues in a number of ways. Virus replication leads directly to host cell lysis. Localized damage to tissues inflammation, etc. Host cell &/or tissues may no longer function properly. Viral proteins are inserted into the host cell membrane. Alters the host cell surface so that it looks foreign . Triggers immune response which attacks foreign tissue. Note: tissue damage caused by viruses often makes the host to infection by other microbes more susceptibility. Eg. secondary bacterial infections: viruses can infect almost every body organ. Different classes of viruses often infect the same organ or tissue eg. nose / throat: Rhinovirus and others: viruses often do not stay at the site where they first contact the host.

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