MCIM 224 Lecture Notes - Lecture 12: Pressure Ulcer, Contact Lens, Ethylene
10 May 2016
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Control of microbes on surfaces vs. control of microbes inside (as with antibiotics, antivirals, etc. ) an infected host. Control = killing of microbes on a surface or physical removal of microbes from a surface or preventing an increase in microbial numbers on a surface. Note: control does not necessarily imply the creation of a sterile which is completely free of living microbes) environment (one. Heat denatures proteins & dna; melts lipids cell death. Moist heat is better than dry heat. Heat penetrates faster when water is present. Water disrupts chemical bonds better protein denaturation eg. boiling water. 10 - 15 min. at 100 c kills bacteria & viruses, but not spores (ie. boiling does not guarantee sterility) (ie. boiling does not guarantee sterility) eg. pressurized steam (via the autoclave) 20 min. of steam @ 15 lbs / inch (= 121 c) kills bacteria and spores (ie. proper autoclaving guarantees sterility)
