MCIM 309 Lecture Notes - Lecture 4: Miscarriage, Dna Virus, Diarrhea

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Hematologic: lymphocytes/macrophages- not permissive of infection, acute phase. Replication of eb, hiv or cmv elicits a large t cell response, Std: hpv, hsv, cytomegalo, hep b,c,d, hiv. Determined by: patients ability to prevent spread. Importance of target tissue: virulence of virus, extent of immunopathology, ability to repair damage, mononucleosis. Flulike symptoms: fever, malaise, anorexia, etc, effects caused by host response to infection. I(cid:374) vire(cid:373)ia, virus" cause release of i(cid:374)terfero(cid:374) a(cid:374)d cytoki(cid:374)es: arthritis. Gastrointestinal: naked capsid, altering function, damage epithelial lining, diarrhea, fecal/oral spread, rota/adeno and coxsakie, or reo/rota/astro/norwalk in adults. Hemorrhagic fever, arthritis"s and exanthems: viral rashes. Slightly raised areas of skin: nodules. Blisters: measles, rubella, herpes, parvo, eb, hsv, papilloma, childhood exanthems. Chikungunya: toga, birds, mammals, aedes mosq. Chronic infections: difficulty in resolving infection. Dna virus: cause latent infections, except. Human cancers: hbv, hcv, ebv, hhv-8, hpv, htlv-1. Immortalize cells: virus containing cells turn into cancer, vaccines available for hpv (see lecture 7) and hbv.

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