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Class Notes for Microbiology and Immunology at University of Saskatchewan

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MCIM 321 Lecture 10: MCIM 321 2019 Section I-10

find more resources at oneclass.com NOTESFOR MICROBIOLOGYANDIMMUNOLOGY321.3821.3 EDITION2019 THEPRINCIPLESOFIMMUNOLOGY 1 find more resources at oneclass.com

Microbiology and Immunology
MCIM 321
Bretscher Peter
MCIM 321 Lecture Notes - Lecture 22: 21 Days, Clonal Deletion, New Born

MICRO 321.3721.3 Session 22 2016 CELLULAR REGULATION OF THE IMMUNE RESPONSE, AND ITS RELATIONSHIP TO SELF TOLERANCE, AUTOIMMUNITY, IMMUNE CLASS REGULATION AND THE GENETICS OF IMMUNORESPONSIVENESS INTRODUCTION: OVERALL REGU...

Microbiology and Immunology
MCIM 321
Bretscher Peter
MCIM 321 Lecture Notes - Lecture 20: Thymus, Immunoglobulin Light Chain, Disulfide

MCIM 321821 Session 20 2016 THE T CELL RECEPTOR AND T CELL SUBSETS IgH GENES ARE NOT PRODUCTIVELY REARRANGED IN T CELLS Tonegawa showed that Ig genes are in a different arrangement in germ cells and in differentiated antib...

Microbiology and Immunology
MCIM 321
Bretscher Peter
MCIM 321 Lecture Notes - Lecture 4: Protease, Immunoglobulin A, Papain

MCIM 321.3821.3 ANTIBODY STRUCTURE AND FUNCTION 2016 Sessions 4, 5 and 6 IDENTIFICATION OF ANTIBODIES IN SERUM We have seen how serum immune to a toxin can inactivate the toxin, and how serum immune to a bacterium can kill...

Microbiology and Immunology
MCIM 321
Bretscher Peter
MCIM 321 Lecture Notes - Lecture 17: Ovalbumin, Lipid Bilayer, Immunogenicity

MCIM 321.3821.3 Sessions 17 and 18 2016 The nature and role of MHC antigens: Molecular nature, the nature of MHCrestriction, alloMHC reactivity, Ir1 genetics and antigen processing H2 RESTRICTION AS SEEN IN THE SPECIFICITY...

Microbiology and Immunology
MCIM 321
Bretscher Peter
MCIM 321 Lecture Notes - Lecture 15: Macrophage, Precipitin, Selectable Marker

MCIM 321.3821.3 Sessions 15 and 16 2016 The nature and role of MHC antigens: Serology, the genetic map of the Major Histocompatibility Complex (MHC), MHCRestriction, and the Generation and Use of Congenic, Transgenic and G...

Microbiology and Immunology
MCIM 321
Bretscher Peter
MCIM 321 Lecture Notes - Lecture 14: Thymidine, Growth Factor, Thymus

MCIM 321.3821.3 Session 14 2016 Nature of, and Assays for, Cell Mediated Immunity and the role of the antigens of the Major Histocompatibility Complex (MHC) in the rapid rejection of grafts THE DISCOVERY OF CELLMEDIATED IM...

Microbiology and Immunology
MCIM 321
Bretscher Peter
MCIM 321 Lecture Notes - Lecture 11: Flagellin, Aluminium Sulfate, White Blood Cell

MCIM 321.3821.3 PRINCIPLES OF IMMUNOLOGY Sessions 11, 12 and 13 2016 ANTIGENICITY, IMMUNOGENICITY AND THE ANTIBODY RESPONSE INTRODUCTION We have seen that an antigen recognized as foreign by the immune system can usually i...

Microbiology and Immunology
MCIM 321
Bretscher Peter
MCIM 321 Lecture Notes - Lecture 11: External Ballistics, Mycobacterium Bovis, T Helper Cell

MCIM 321.3821.3 PRINCIPLES OF IMMUNOLOGY Sessions 11, 12 and 13 2016 ANTIGENICITY, IMMUNOGENICITY AND THE ANTIBODY RESPONSE INTRODUCTION We have seen that an antigen recognized as foreign by the immune system can usually i...

Microbiology and Immunology
MCIM 321
Bretscher Peter
MCIM 321 Lecture Notes - Lecture 10: Immunoglobulin A, Mast Cell, Neutrophil

MCIM 321.3 821.3 PRINCIPLES OF IMMUNOLOGY Session 10, 2016 CELLS OF THE IMMUNE SYSTEM, LYMPHOPOIESIS, THE STRUCTURE OF LYMPHOID ORGANS AND LYMPHOCYTE RECIRCULATION LYMPHOCYTES, present in blood, are for the most part small...

Microbiology and Immunology
MCIM 321
Bretscher Peter
MCIM 321 Lecture Notes - Lecture 8: Lysis, Rag1, Agarose Gel Electrophoresis

MCIM 321.3821.3 Principles of Immunology 2016 Sessions 8 9 GENERATION OF THE DIVERSITY OF ANTIBODY GENES AMINOACID SEQUENCE INFORMATION The decisive information required to decide between germline and somatic theories for...

Microbiology and Immunology
MCIM 321
Bretscher Peter
MCIM 321 Lecture Notes - Lecture 7: Syngenic, Hapten, Epitope

MCIM 321.3821.3 Session 7, 2016 CLONAL SELECTION AND THE ORIGIN OF ANTIBODY GENES ORIGIN OF CLONAL SELECTION THEORY In 1955, Jerne put forward his selection theory of antibody formation, the first time a selection theory w...

Microbiology and Immunology
MCIM 321
Bretscher Peter
MCIM 321 Lecture Notes - Lecture 5: Phagocytosis, F1 Hybrid, List Of Breaking Bad And Better Call Saul Characters

CONSTANT AND VARIABLE REGIONS AND DOMAIN STRUCTURE OF IMMUNOGLOBULINS Hilschmann and Craig were the first to sequence light (kappa) chains from myeloma proteins. This revealed the light chain to consist of two roughly equa...

Microbiology and Immunology
MCIM 321
Bretscher Peter
MCIM 321 Lecture Notes - Lecture 3: Interferon, Gram-Negative Bacteria, Opsonin

MCIM 321.3821.3 PRINCIPLES OF IMMUNOLOGY Session 3 2016 ADAPTIVE IMMUNITY AND INNATE DEFENCE MECHANISMS CLASSIFICATION AND PROPERTIES OF DEFENCE MECHANISMS It is a matter of common experience that abrasions often fail to d...

Microbiology and Immunology
MCIM 321
Bretscher Peter
MCIM 321 Lecture Notes - Lecture 2: Replica Plating, Antigen, Epitope

MCIM 321.3821.3 PRINCIPLES OF IMMUNOLOGY 2016 Sessions 1 and 2 HISTORICAL INTRODUCTION AND OVERVIEW OF THE COURSE This introduction provides a brief historical sketch of how immunology developed up to the beginning of the ...

Microbiology and Immunology
MCIM 321
Bretscher Peter

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