PATH 205.3 Lecture Notes - Lecture 4: Appendicitis, Wound Healing, Gross Examination

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19 Sep 2018
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Pathology of inflammation: several forms of inflammation can be recognized on gross examination of the affected tissues. These organs can also be visualized without surgery by using fiberoptic instruments, such as a laparoscope, used to inspect the abdominal cavity: finally, in the autopsy room, various manifestations of inflammation can be observed in cadavers. Serous inflammation: mild, exudation of serum, early stages of most inflammations, typical of viral infections ie. skin vesicles (herpes virus, exudate rich in fibrin. Indicates more severe inflammation: e. g. strep throat, seen in many bacterial infections, resolves more slowly (requires macrophages to lyze fibrin, may be organized (space filled with blood vessels, may form fibrous (scar) tissue. Purulent inflammation: usually caused by bacterial infection (staph, strep, viscous yellow fluid filled with tissue debris and dying pmns (pus) Abscess = localized collection of pus within an organ or tissue, etc. (mucosa: closed pocket of purulent inflammatory exudate (pus, usually requires surgical drainage.

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